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nucleocapsid protein

" in MedChemExpress (MCE) Product Catalog:

By Targets:	HIV (2) Influenza Virus (2) RSV (1) SARS-CoV (4)
By Research Areas:	Infection (9)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145560

Claficapavir A1752	HIV	Infection
Claficapavir (A1752) is a specific **nucleocapsid protein (NC) inhibitor with an IC₅₀** around 1 μM. Claficapavir strongly binds the HIV-1 NC (K_d=20 nM) thereby inhibiting the chaperone properties of NC and leading to good antiviral activity against the HIV-1 .

HY-12993

RSV604 2 Publications Verification A-60444	RSV	Infection
RSV604 (A-60444) is an inhibitor of respiratory syncytial virus (RSV) replication. RSV604 targets the **nucleocapsid protein, with a K_d of 1.6 μM. RSV604 displays submicromolar activity against numerous clinical isolates of both the A and B subtypes of RSV (average EC₅₀**s=0.8 μM) .

HY-143417

SARS-CoV-2-IN-16	SARS-CoV	Infection
SARS-CoV-2-IN-16 (Compound 12) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-16 exhibits potent anti-viral activity with the EC₅₀ of 3.69 μM. SARS-CoV-2-IN-16 binds to NPro with the low K_D value of 7.82 μM, suggesting that SARS-CoV-2-IN-16 is a potent NPro ligand .

HY-143418

SARS-CoV-2-IN-17	SARS-CoV	Infection
SARS-CoV-2-IN-17 (Compound 16) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-17 exhibits potent anti-viral activity with the EC₅₀ of 2.18 μM. SARS-CoV-2-IN-17 binds to NPro with the low K_D value of 7.82 μM, suggesting that SARS-CoV-2-IN-17 is a potent NPro ligand .

HY-P0304

CEF4

Influenza Virus Infection

CEF4 is a peptide that corresponds to aa 342-351 of the influenza A virus nucleocapsid protein.
HY-P0313

CEF6

Influenza Virus Infection

CEF6 is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein.

CEF4	Influenza Virus	Infection
CEF4 is a peptide that corresponds to aa 342-351 of the influenza A virus nucleocapsid protein.

CEF6	Influenza Virus	Infection
CEF6 is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein.

HY-102077

SAMT-247	HIV	Infection
SAMT-247 is a microbicide that selectively inactivate the viral nucleocapsid protein NCp7, causing zinc ejection and preventing RNA encapsidation. SAMT-247 shows good antiviral activity .

HY-156346

HCoV-OC43-IN-1	SARS-CoV	Infection
HCoV-OC43-IN-1 (Compound IV-16) is a coronavirus HCoV-OC43 inhibitor. HCoV-OC43-IN-1 has antiviral efficacy (EC₅₀: 90 nM). HCoV-OC43-IN-1 inhibits the mRNA level and expression of viral nucleocapsid protein (NP) .

HY-N11902

1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one	SARS-CoV	Infection
1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one exhibits excellent antiviral activity against HCoV-OC43 and SARS-CoV-2,with EC₅₀ values of 0.16 μM and 0.17 μM, respectively .

HY-N1870

1β-Hydroxy-4(15),5E,10(14)-germacratriene
1β-Hydroxy-4(15),5E,10(14)-germacratriene (compound 17) is a sesquiterpenoids that can be isolated from Chrysanthemum indicum.1β-Hydroxy-4(15),5E,10(14)-germacratriene significantly reduces PEDV nucleocapsid and spike protein synthesis.1β-Hydroxy-4(15),5E,10(14)-germacratriene shows various biological properties, such as antibacterial, antioxidant, and anti-inflammatory .

Cat. No.	Product Name	Target	Research Area

HY-P0304

CEF4

Influenza Virus Infection

CEF4 is a peptide that corresponds to aa 342-351 of the influenza A virus nucleocapsid protein.
HY-P0313

CEF6

Influenza Virus Infection

CEF6 is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein.

CEF4	Influenza Virus	Infection
CEF4 is a peptide that corresponds to aa 342-351 of the influenza A virus nucleocapsid protein.

CEF6	Influenza Virus	Infection
CEF6 is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein.

CEF4	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Influenza Virus
CEF4 is a peptide that corresponds to aa 342-351 of the influenza A virus nucleocapsid protein.

1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one	Structural Classification Source classification Phenols Polyphenols Plants Curcuma longa Zingiberaceae	SARS-CoV
1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one exhibits excellent antiviral activity against HCoV-OC43 and SARS-CoV-2,with EC₅₀ values of 0.16 μM and 0.17 μM, respectively .

Species:	Virus (17) Human (1)
Tag:	SUMO (3) His (18) Avi (4)
Source:	Sf9 insect cells (4) E. coli (14)

Cat. No.	Compare	Product Name	Species	Source

HY-P72285

	Nucleoprotein/NP Protein, Influenza A virus H3N2 (His-SUMO) NP; Nucleoprotein; nucleocapsid protein; protein N	Virus	E. coli
	The Nucleoprotein/NP Protein in the influenza virus is crucial for viral replication and transcription. It binds to viral RNA, forming a ribonucleoprotein complex necessary for genome replication. NP Protein also interacts with host proteins, facilitating viral pathogenesis and immune evasion. Understanding NP Protein's functions can aid in developing antiviral strategies against influenza infections. Nucleoprotein/NP Protein, Influenza A virus H3N2 (His-SUMO) is the recombinant Virus-derived Nucleoprotein/NP protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of Nucleoprotein/NP Protein, Influenza A virus H3N2 (His-SUMO) is 498 a.a., with molecular weight of ~72.0 kDa.

HY-P72283

	Nucleoprotein/NP Protein, Influenza B virus (His-SUMO) NPNucleoprotein; nucleocapsid protein; protein N	Virus	E. coli
	Nucleoprotein (NP) protects viral RNA and serves as a replication template. Nucleoprotein/NP Protein, Influenza B virus (His-SUMO) is the recombinant Virus-derived Nucleoprotein/NP protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of Nucleoprotein/NP Protein, Influenza B virus (His-SUMO) is 560 a.a., with molecular weight of ~78.0 kDa.

HY-P72034

	*SARS-CoV-2 Nucleocapsid* Protein, Human (His)** nucleocapsid protein	Human	E. coli
	The SARS-CoV-2 nucleocapsid protein plays a crucial role in assembling the virion, forming the helical ribonucleocapsid (RNP), and interacting with the viral genome and membrane protein M. In addition to its structural function, it also enhances subgenomic viral RNA transcription and overall replication. SARS-CoV-2 Nucleocapsid Protein, Human (His) is the recombinant human-derived SARS-CoV-2 Nucleocapsid protein, expressed by E. coli , with N-6*His labeled tag. The total length of SARS-CoV-2 Nucleocapsid Protein, Human (His) is 419 a.a., with molecular weight of ~48 kDa.

HY-P78111

	Nucleocapsid Protein CTD domain, Virus (His-Avi) nucleocapsid; NP; NC	Virus	E. coli
	SARS-CoV-2 S1 Protein, in its Spike protein S1 form, initiates infection by attaching the virion to the cell membrane through host receptor interaction. Simultaneously, Spike protein S2' acts as a viral fusion peptide, revealing itself after S2 cleavage during virus endocytosis. Nucleocapsid Protein CTD domain, Virus (His-Avi) is the recombinant Virus-derived Nucleocapsid protein CTD domain, Virus, expressed by E. coli , with N-His, N-Avi labeled tag. The total length of Nucleocapsid Protein CTD domain, Virus (His-Avi) is 122 a.a., with molecular weight of ~17 kDa.

HY-P7437

	Nucleocapsid Protein (His) 2019-nCoV coronavirus NP protein; 2019-nCoV np protein; 2019-nCoV novel coronavirus Nucleoprotein protein	Virus	E. coli
	Nucleocapsid Protein (His) expressed by E. coli systems. Nucleocapsid Protein is required for coronavirus RNA synthesis and has RNA chaperone activity.

HY-P7438

	Nucleocapsid Protein NTD domain, Virus (His) 2019-nCoV coronavirus NP protein; 2019-nCoV np protein; 2019-nCoV novel coronavirus Nucleoprotein protein	Virus	E. coli
	Nucleocapsid Protein NTD domain, Virus (His) is the N-terminal RNA-binding domain (NTD) of nucleocapsid protein in coronaviruses. Nucleocapsid Protein NTD domain has highly conserved residues in the centre, which is identified as the RNA-binding site.

HY-P7439

	Nucleocapsid Protein CTD domain, Virus (His) 2019-nCoV coronavirus NP protein; 2019-nCoV np protein; 2019-nCoV novel coronavirus Nucleoprotein protein	Virus	E. coli
	Nucleocapsid Protein CTD domain, Virus (His) is the C-terminal dimerisation domain (CTD) of nucleocapsid protein in coronaviruses. Nucleocapsid Protein CTD domain has a stronger nucleic acid-binding activity than the NTD, which could be a nucleic acid-binding site .

HY-P78276

	*SARS-COV-2 Nucleocapsid* Protein (His-Avi)** nucleocapsid; NP; NC	Virus	E. coli
	The SARS-CoV-2 nucleocapsid protein plays a crucial role in assembling the virion, forming the helical ribonucleocapsid (RNP), and interacting with the viral genome and membrane protein M. In addition to its structural function, it also enhances subgenomic viral RNA transcription and overall replication. SARS-COV-2 Nucleocapsid Protein (His-Avi) is the recombinant Virus-derived SARS-COV-2 Nucleocapsid protein, expressed by E. coli , with N-His, N-Avi labeled tag. The total length of SARS-COV-2 Nucleocapsid Protein (His-Avi) is 418 a.a., with molecular weight of ~48.9 kDa.

HY-P78277

	*SARS-COV-2 Nucleocapsid* Protein (Bioytinylated, His-Avi)** nucleocapsid; NP; NC	Virus	E. coli
	The SARS-CoV-2 nucleocapsid protein plays a crucial role in assembling the virion, forming the helical ribonucleocapsid (RNP), and interacting with the viral genome and membrane protein M. In addition to its structural function, it also enhances subgenomic viral RNA transcription and overall replication. SARS-COV-2 Nucleocapsid Protein (Bioytinylated, His-Avi) is the recombinant Virus-derived SARS-COV-2 Nucleocapsid protein, expressed by E. coli , with N-His, N-Avi labeled tag. The total length of SARS-COV-2 Nucleocapsid Protein (Bioytinylated, His-Avi) is 418 a.a., with molecular weight of 50-52 kDa.

HY-P78186

	*SARS-CoV-2 Nucleocapsid* Protein NTD domain (His-Avi)** nucleocapsid; NP; NC	Virus	E. coli
	SARS-CoV-2 S1 Protein, in its Spike protein S1 form, initiates infection by attaching the virion to the cell membrane through host receptor interaction. Simultaneously, Spike protein S2' acts as a viral fusion peptide, revealing itself after S2 cleavage during virus endocytosis. SARS-CoV-2 Nucleocapsid Protein NTD domain (His-Avi) is the recombinant Virus-derived SARS-CoV-2 Nucleocapsid protein NTD domain, expressed by E. coli , with N-His, N-Avi labeled tag. The total length of SARS-CoV-2 Nucleocapsid Protein NTD domain (His-Avi) is 117 a.a., with molecular weight of ~16.3 kDa.

HY-P74443

	*SARS-CoV-2 Nucleocapsid* Protein (Omicron, B.1.1.529, His)** N protein; nucleocapsid	Virus	E. coli
	Nucleoprotein/NP Protein is essential for viral replication and transcription. Nucleoprotein/NP Protein binds to viral RNA to form a ribonucleoprotein complex required for genome replication. Nucleoprotein/NP Protein promotes NLRP3 inflammasome activation to induce excessive inflammation. SARS-CoV-2 Nucleocapsid Protein (Omicron, B.1.1.529, His) is the recombinant Virus-derived SARS-CoV-2 Nucleocapsid protein, expressed by E. coli , with N-His labeled tag. The total length of SARS-CoV-2 Nucleocapsid Protein (Omicron, B.1.1.529, His) is 419 a.a., with molecular weight of ~46.31 kDa.

HY-P76965

	Nucleocapsid/NP Protein, HTNV (sf9, His) Hantaan virus HTNV (strain 84FLi) nucleocapsid / NP protein (His)	Virus	Sf9 insect cells
	Nucleocapsid/NP belongs to the hantavirus nucleocapsid protein family. Nucleocapsid/NP Protein, HTNV (sf9, His) is the recombinant Virus-derived Nucleocapsid/NP protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of Nucleocapsid/NP Protein, HTNV (sf9, His) is 429 a.a., with molecular weight of ~49.7 KDa.

HY-P77382

	Nucleoprotein/NP Protein, HCoV-NL63 (His) Human coronavirus (HCoV-NL63) nucleocapsid protein (His)	Virus	E. coli
	HCoV-NL63 Nucleoprotein (NP, N) is a homodimer with nonspecific binding activity toward nucleic acids. NP packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly, enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication through its interactions with the viral genome and membrane protein M. Nucleoprotein/NP Protein, HCoV-NL63 (His) is the recombinant Virus-derived Nucleoprotein/NP protein, expressed by E. coli , with N-His labeled tag. The total length of Nucleoprotein/NP Protein, HCoV-NL63 (His) is 377 a.a., with molecular weight of ~43.21 KDa.

HY-P77385

	HCoV-OC43 Nucleoprotein/NP Protein (His) Human coronavirus (HCoV-OC43) nucleocapsid protein (His)	Virus	E. coli
	HCoV-OC43 Nucleoprotein (NP, N) is a homodimer with nonspecific binding activity toward nucleic acids. NP packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly, enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication through its interactions with the viral genome and membrane protein M. HCoV-OC43 Nucleoprotein/NP Protein (His) is the recombinant Virus-derived HCoV-OC43 Nucleoprotein/NP protein, expressed by E. coli , with N-His labeled tag. The total length of HCoV-OC43 Nucleoprotein/NP Protein (His) is 448 a.a., with molecular weight of ~50.43 KDa.

HY-P75886

	Nucleocapsid/NP Protein, H7N9 (R4NE06, sf9, His) Influenza A H7N9 (A/Shanghai/2/2013) nucleocapsid / NP protein (His)	Virus	Sf9 insect cells
	Nucleoprotein/NP is critical in the influenza virus life cycle, encapsulating the negative-strand viral RNA to form a ribonucleoprotein (RNP) template. The nuclear localization signal of NP guides RNP into the host cell nucleus through α/β import. Nucleocapsid/NP Protein, H7N9 (R4NE06, sf9, His) is the recombinant Virus-derived Nucleocapsid/NP protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Nucleocapsid/NP Protein, H7N9 (R4NE06, sf9, His) is 498 a.a., with molecular weight of ~57 kDa.

HY-P75885

	Nucleocapsid/NP Protein, H7N9 (AHZ59787, sf9, His) Influenza A H7N9 (A/Anhui/1-BALF_RG6/2013) nucleocapsid / NP protein (His)	Virus	Sf9 insect cells
	Nucleocapsid protein in many coronaviruses is highly conserved, immunogenic, and abundantly expressed during infection. Nucleocapsid/NP Protein, H7N9 (AHZ59787, sf9, His) is the recombinant Virus-derived Nucleocapsid/NP protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Nucleocapsid/NP Protein, H7N9 (AHZ59787, sf9, His) is 498 a.a., with molecular weight of ~55 kDa.

HY-P74754

	MERS-CoV Nucleoprotein/NP Protein (sf9, His) MERS-CoV coronavirus NP protein; MERS-CoV coronavirus nucleocapsid protein	Virus	Sf9 insect cells
	MERS-CoV Nucleoprotein/NP Protein is a phosphorylated basic protein and the second largest structural protein of MERS-CoV, containing 413 amino acid residues. The Nucleoprotein combines with the RNA genome to form a nucleocapsid, which is important in viral replication and assembly. In addition, Nucleoprotein plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. MERS-CoV Nucleoprotein/NP Protein (sf9, His) is the recombinant Virus-derived MERS-CoV Nucleoprotein/NP protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of MERS-CoV Nucleoprotein/NP Protein (sf9, His) is 413 a.a., with molecular weight of ~46.51 kDa.

HY-P72284

	Nucleoprotein/NP Protein, Influenza A virus H1N1 (His-SUMO) SARS-CoV coronavirus NP protein; SARS-CoV np protein; SARS-CoV novel coronavirus Nucleoprotein protein	Virus	E. coli
	Nucleoprotein/NP Protein, a key component of the influenza virus, plays a vital role in viral replication and transcription. It binds to viral RNA, forming a ribonucleoprotein complex essential for viral genome replication. NP Protein also interacts with host proteins, contributing to viral pathogenesis and immune evasion. Understanding the functions of NP Protein can aid in the development of antiviral strategies against influenza infections. Nucleoprotein/NP Protein, Influenza A virus H1N1 (His-SUMO) is the recombinant Virus-derived Nucleoprotein/NP protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of Nucleoprotein/NP Protein, Influenza A virus H1N1 (His-SUMO) is 498 a.a., with molecular weight of ~72.1 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P81081

SARS-CoV-2 (2019-nCoV) Nucleocapsid Antibody (YA918) SARS-CoV-2 nucleocapsid protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N protein; novel coronavirus nucleocapsid protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N protein; 2019 ncov N protein; 2019-nCoV nucleocapsid protein.	WB; ELISA
SARS-CoV-2 (2019-nCoV) Nucleocapsid Antibody (YA918) is an unconjugated, approximately 46 kDa, mouse-derived, anti-SARS-CoV-2 (2019-nCoV) Nucleocapsid (YA918) monoclonal antibody. SARS-CoV-2 (2019-nCoV) Nucleocapsid Antibody (YA918) can be used for: WB, ELISA expriments in background without labeling.

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nucleocapsid protein

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